Metabolically Neutral Obesity: Terminology, Prevalence, And Meaning

Determining the leptin level in patients with abdominal obesity without signs of insulin resistance is necessary for stratifying into groups normal (metabolically neutral obesity) and increased adipokine activity. Objective — To compare prevalence metabolic disorders cardiovascular remodeling young middle-aged men "metabolically healthy" neutral" obesity. Material methods observational sample survey 590 aged 38.5±5.6 years was conducted. Average body weight assessed on301 (the control group). Obesity determined 289 patients: among them, criteria syndrome were diagnosed 134 study participants, metabolically healthy (MHO) 155 men, 86 from MHO levels <3.5 ng/ml constituted group. All evaluated by a lipidogram, adipokine, glycemic profiles, ultrasound examination heart carotid arteries. Results Criteria determined: gain >30 kg/m2 presence no more than two ng/ml. The type characterized better lipid profile, which confirmed lower frequency dyslipidemia (1.7 times); prediabetes 7% half as low obesity; atherosclerosis arteries 1.5 times less common Conclusion selection justified since it allows us to determine stage disease at still minimal non-drug prevention necessary.